Black's Medical Dictionary (Writing Handbook) By Gordon Macpherson
The forty-first edition gives over 5000 definitions and descriptions of medical terms and concepts accompanied by appendices on important subjects such as Health Economics, Complementary and Alternative Medicine, Common Medical Tests and an address list of support and professional organisations. All material has been checked and updated with new and substantially revised entries on: abortion, anaesthetics, assisted conception, breast screening, chronic fatigue syndrome (ME), clinical guidelines, clinical trials, evidence-based medicine, general practice, Gulf War syndrome, menopause, psychosomatic medicine.DownloadLink 1
Fundamental Neuroscience for Basic and Clinical Applications by Duane E. HainesA richly illustrated, clinically oriented textbook with well-balanced coverage of both neurophysiology and neuroanatomy provides all the knowledge you need for Board exam preparation and practice! This 3rd Edition offers meticulous updates from cover to cover ... a new, more user-friendly page layout ... 300 USMLE-style review questions, with answers and rationales ...
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Basislehrbuch Innere MedizinDie Textpassagen sind übersichtlich und gut lesbar und werden durch viele gut gestaltete Abbildungen und Tabellen ergänzt, die das Lernen erleichtern. Über 1000 Übersichtskästen helfen den Stoff zu gliedern. Med-Info, Fachschaft Medizin Klinik der Universität Bonn Alle Themengebiete werden in für Studenten in umfassender Weise bearbeitet und mit sehr gutem didaktischen Konzept dargestellt. (...) Das Basislehrbuch Innere Medizin macht Spaß beim Lernen. Es ist sowohl für diejenigen geeignet, die sich in der konservativen Medizin wiederfindenDownloadLink 1
Process Scale Bioseparations for the Biopharmaceutical Industry
The biopharmaceutical industry has become an increasingly important player in the global economy, and the success of these products depends on the development and implementation of cost-effective, robust and scaleable production processes. Bioseparations-also called downstream processing- can be a key source of competitive advantageto biopharmaceutical developers.
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Atlas der Anatomie By Frank H Netter von Urban"Netter's Atlas of Human Anatomy" is the most loved and best selling anatomy atlas in the English language. In over 530 beautifully coloured and easily understood illustrations, it teaches the complete human body with unsurpassed clarity and accuracy. This new edition features 45 revised, 290 relabelled and 17 wholly new plates, drawn fully in the tradition of Frank Netter, and includes more imaging and clinical images than ever before. Six Consulting Editors have worked together to ensure the new edition's accuracy and usefulness in the lecture theatre, classroom and dissection lab.DownloadLink 1
Intratumor Diversity and Clonal Evolution in Cancer By DavidGisselsson
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Proteasome Inhibitors in Cancer Therapy (Cancer Drug Discovery and Development) by Julian AdamsImmediately upon the discovery some ten years ago that inhibition of the proteasome in cultured cells, mostly of tumor origin, caused the programmed cell death machinery to ramp up, it became imperative to investigate proteasome inhibition as a possible treatment for human cancers. In Proteasome Inhibitors in Cancer Therapy, Julian Adams, the leader in developing the field, brings together a panel of highly experienced academic and pharmaceutical investigators to take stock of the remarkable work that has been accomplished to date, and examine emerging therapeutic possibilities for proteasome inhibitors in cancer.
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Germ Cell Tumor by Angabin MatinThe book aims to provide an overview of current knowledge regarding germ cell tumors. It deals with the clinical presentations, treatment modalities, the biology and genetics of germ cell tumors in children and adults. Most chapters are focused on testicular germ cell tumors whose incidence has been increasing in young males. Included are reviews on the pathogenesis, risk factors, diagnosis and treatment regimens applied to precursor, pre-invasive lesions as well as to seminomatous and non-seminomatous germ cell tumors of the testes. In addition, a review is included on the diagnosis and current management options for intracranial germ cell tumors in children. Authors have also contributed articles on the genetics and epigenetics of germ cell tumor development in humans and in the mouse model system. This book will be of interest to scientists, physicians and lay readers wishing to review recent developments in the field of germ cell cancers. Download
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Handbook of Individual Differences in Cognition: Attention, Memory, and Executive Control By Aleksandra Gruszka, Gerald Matthews
Publisher: Springer 2010 | 600 Pages | ISBN: 1441912096 | PDF | 5 MB
As cognitive models of behavior continue to evolve, the mechanics of cognitive exceptionality, with its range of individual variations in abilities and performance, remains a challenge to psychology. Reaching beyond the standard view of exceptional cognition equaling superior intelligence, the Handbook of Individual Differences in Cognition examines the latest findings from psychobiology, cognitive psychology, and neuroscience, for a comprehensive state-of-the-art volume.
Breaking down cognition in terms of attentional mechanisms, working memory, and higher-order processing, contributors discuss general models of cognition and personality. Chapter authors build on this foundation as they revisit current theory in such areas as processing effort and general arousal and examine emerging methods in individual differences research, including new data on the role of brain plasticity in cognitive function. The possibility of a unified theory of individual differences in cognitive ability and the extent to which these variables may account for real-world competencies are emphasized, and commentary chapters offer suggestions for further research priorities.
Coverage highlights include:
The relationship between cognition and temperamental traits.
The development of autobiographical memory.
Anxiety and attentional control.
The neurophysiology of gender differences in cognitive ability.
Intelligence and cognitive control.
Individual differences in dual task coordination.
The effects of subclinical depression on attention, memory, and reasoning.
Mood as a shaper of information.
Researchers, clinicians, and graduate students in psychology and cognitive sciences, including clinical psychology and neuropsychology, personality and social psychology, neuroscience, and education, will find the Handbook of Individual Differences in Cognition an expert guide to the field as it currently stands and to its agenda for the future.
Fundamentals of Medicinal Chemistry
Wiley | December 2, 2003 | ISBN-10: 0470843071 | 302 pages | PDF | 3.8 mb
The title begins by reviewing the structures and nomenclature of the more common classes of naturally occurring compounds found in biological organisms. An overview of medicinal chemistry is followed by chapters covering the discovery and design of drugs, pharmacokinetics and drug metabolism, The book concludes with a chapter on organic synthesis, followed by a brief look at drug development from the research stage through to marketing the final product.DownloadDownload
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Gareth Thomas, "Medicinal Chemistry: An Introduction"
Wiley-Interscience 2008 | ISBN-10: 0470025972 | 646 Pages | PDF | 8 MB
Product DescriptionMedicinal Chemistry: An Introduction, Second Edition provides a comprehensive, balanced introduction to this evolving and multidisciplinary area of research. Building on the success of the First Edition, this edition has been completely revised and updated to include the latest developments in the field. Written in an accessible style, Medicinal Chemistry: An Introduction, Second Edition carefully explains fundamental principles, assuming little in the way of prior knowledge. The book focuses on the chemical principles used for drug discovery and design covering physiology and biology where relevant. It opens with a broad overview of the subject with subsequent chapters examining topics in greater depth. From the reviews of the First Edition: "It contains a wealth of information in a compact form" ANGEWANDTE CHEMIE, INTERNATIONAL EDITION "Medicinal Chemistry is certainly a text I would chose to teach from for undergraduates. It fills a unique niche in the market place." PHYSICAL SCIENCES AND EDUCATIONAL REVIEWSDownload
Carmen Avendano, J. Carlos Menendez "Medicinal Chemistry of Anticancer Drugs"
Elsevier Science | 2008-04-16 | ISBN: 0444528245 | 400 pages | PDF | 10,8 MB
Antitumour chemotherapy is nowadays a very active field of research, and a huge amount of information on the topic is generated every year. Although many books are available that deal with clinical aspects of cancer chemotherapy, this book addresses the need for an updated treatment from the point of view of medicinal chemistry and drug design. Cytotoxic chemotherapy is gradually being supplemented by a new generation of drugs that recognize specific targets on the surface or inside cancer cells. These therapies are in their infancy, but they hold promise of more effective therapies with fewer side effects. Resistance to antitumour drugs is another important but normally neglected field. The focus of Medicinal Chemistry of Anticancer Drugs is on the mechanism of action of antitumour drugs from the molecular point of view and on the relationship between chemical structure and chemical and biochemical reactivity of antitumour agents, aiming at the rationalization of the action of this type of drugs, which would allow the design of new active structures.* Presents information in a clear and concise way using a large number of figures* Historical background provides insights on how the process of drug discovery in the anticancer field has evolved* Extensive references to primary literature
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Introduction to Medicinal Chemistry: How Drugs Act and Why
Publisher: Wiley-VCH | pages: 736 | 1996 | ISBN: 0471185450 | DJVU | 22,5 mb
This work brigdges the compartmentalized undergraduate organic and biochemistry and biology subjects to the pharmacology and the clinical areas a modern pharmacy practice requires. The changes and constantly increasing responsibilities of today's pharmacist have dictated a restructuring of the pharmacy curriculum, including individual course content. This book reflects and addresses these developments. This is a well-written work that covers most major areas of pharmaceutical research. The text is presented in a logical and concise fashion being divided into chapters based upon therapeutic topic. This makes the work very useful for teaching a course in medicinal chemistry since therapeutic areas can be separately covered without having to make use of the entire book which overall contains a tremendous amount of information. This book is a significant contribution to understanding what medicinal chemistry is and how this science is used to develop new therapeutic agents.
The Practice of Medicinal Chemistry, Third Edition
Publisher: Academic Press | ISBN: 0123741947 | edition 2008 | PDF | 982 pages | 24,6 mb
Now in its third edition, this classic reference is the one-stop-shop for information on the foundations of medicinal chemistry for pharmaceutical researchers who are involved in drug development & discovery but who do not have a background in medicinal chemistry. Wermuth aids pharmaceutical researchers and chemists in making faster, more accurate identifications of the active substances that could potentially treat the disorder they are researching. New chapters on Drug Absorption & Transport give pharmaceutical scientists information on how potential drugs can move through the drug discovery/development phases more quickly. This third edition still stands as the only source for practical aspects of medicinal chemistry by focusing on the daily problems met by the medicinal chemist in drug discovery.
Graham L. Patrick - An Introduction to Medicinal Chemistry, 4th EditionOxford University Press | 2009 | ISBN: 0199234477 | Pages: 752 | DJVU | 21.2 MB
The average person in the UK will take more than 14,000 pills over the course of their life, yet few people consider the long road of development that has made that drug work without being toxic. An Introduction to Medicinal Chemistry presents the field in an engaging style that is very accessible to students.
Medicinal chemistry is a fast-moving field whose continuous new developments have far-reaching implications for world health. As such, this text presents a complete course in medicinal
chemistry, from first principles of drug action, to design and development, to specific drugs from HIV inhibitors to painkillers.
The book builds on the history of drug development, but does not assume much background knowledge. The focus is on building upon the understandings of the molecular function of drugs, and from there, taking a broad overview of the topical issues and most frequently used techniques.
An Introduction to Medicinal Chemistry remains a leading text for the growing number of medicinal chemistry courses internationally, especially as modules in medical chemistry become a more popular option on chemistry courses. With enhanced attention to the pedagogical details such as key points and boxes, as well as having specific case studies highlighted in distinct sections, Patrick's new edition enables a full understanding of the subject and a clear idea of where the field is heading.
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Ashutosh Kar "Advanced Practical Medicinal Chemistry"
New Age International (P) Ltd. | 2004 | ISBN: 8122415393 | 332 pages | PDF | 2,5 MB
The present compendium on Advanced Practical Medicinal Chemistry is designed specifically to serve as a text-cum-reference book not only intended for the advanced undergraduate and graduate students of Pharmacy specializing in pharmaceutical chemistry but also for the bulk-drug industrial researchers and academics who work intimately with medicinal compounds. It mainly comprises of four comprehensive chapters. First chapter is entirely devoted to Safety in Chemical Laboratory, which is an absolute must for each medicinal chemist. Second chapter is on Drug Synthesis and concentrates on three vital aspects, namely : conceptualization of a synthesis, reaction variants, and stereochemistry. Third chapter exclusively deals with Performing the Reactions and entails the wide range of latest laboratory techniques used in a good chemical laboratory to facilitate synthesis of drugs.
Fourth chapter is particularly focused and earmarked to Synthesis of Medicinal Compounds, and essentially include various cardinal aspects, such as :types of chemical reactions, organic name reactions (ONRs), and selected medicinal compounds. A galaxy of eighty carefully chosen medicinal compounds have been presented in an original unique style comprising of: chemical structure, synonym (s)/chemical name(s) theory chemicals required procedure precautions recrystallization theoretical yield/practical yield physical parameters uses, and questions for viva-voce.
It is hoped that Advanced Practical Medicinal Chemistry would certainly help to bridge existing gap and fill up the long needed vacuum in the synthesis of drugs in pharmaceutical chemistry departments, academics and bulk-drug industries, and may provide the basis for meaningful productive group discussions of synthetic problems on a broader perspective.
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Graham L. Patrick, "An Introduction to Medicinal Chemistry"
Oxford University Press, USA; | ISBN-10: 0199275009 | 768 pages | PDF | 10,4 Mb
Review: `Review from previous edition "There is excellent all-round coverage here for both undergraduates and postgraduate researchers ... This is a textbook which should be used throughout all medicinal chemistry courses."' Chemistry and Industry 2002`"In summary Patrick is in my opinion the best text support for a Medicinal Chemistry programme and it continues to be better and better with each review..."' Stuart Warriner, University of Leeds, 2004 Book DescriptionMany of us think nothing of taking a painkiller to ease a headache, or to relieve the symptoms of 'flu. But how do drugs have their effect in the human body? How are new drugs discovered and designed to be as effective as possible? An Introduction to Medicinal Chemistry offers an engaging insight into the one field of chemistry that arguably has the greatest impact on our quality of life than any other. Newly structured into four parts, the book opens in Part A with an introduction to pharmacodynamics and pharmacokinetics. Pharmacodynamics considers the types of molecular targets used by drugs, the interactions which are involved when a drug meets that target, and the consequences of those interactions. Pharmacokinetics considers the issues involved in a drug reaching its target in the first place. Part B goes on to examine the general principles and strategies involved in discovering and designing new drugs and developing them for the marketplace, while Part C looks at particular 'tools of the trade' which are invaluable in those processes. Finally, Part D covers a selection of specific topics within medicinal chemistry. Reflecting a change in emphasis in medicinal chemistry research, this Part takes us from the largely trial-and-error approach to drug design to the rational approach, and explores the most recent advances in molecular biology and genetics which have revolutionised drug design. With a striking new two-colour text design, and greatly enriched learning features, the third edition conveys the fascination of working in a field which overlaps the disciplines of chemistry, biochemistry, physiology, microbiology, cell biology, and pharmacology. A must-have textbook for any student of medicinal chemistry. Online Resource Centre - Figures available to download, to facilitate lecture preparation - 3D molecular structures, to enable students to visualise key structures in an interactive way - Multiple choice questions with answers, to support and encourage independent learningDownload
Donald J. Abraham
Burger's Medicinal Chemistry and Drug Discovery, 6th Edition (6 Volume Set)
Set ISBN: 0471370320 | Archived in individual volumes | 234.98 mb total | Download link to RS folder
This new sixth edition of Burgers Medicinal Chemistry and Drug Discovery offers several new and unique features. For the first time, all volumes are structured entirely according to content and published simultaneously to provide broad coverage of medicinal chemistry and drug discovery for new or experienced medicinal chemists, biologists, pharmacologists and molecular biologists. This includes a current and global perspective of drug design, and drug development.
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Burger's Medicinal Chemistry (234.98 mb total)Contents of Rapidshare folder:
Volume 1 : Drug Discovery
ISBN: 0471270903 | Wiley-Interscience, 2003 | 960 pgs | 48.23 mb
Volume 2: Drug Discovery and Drug Development
ISBN 0471370282 | Wiley-Interscience, 2003 | 832 pgs | 38.50 mb
Volume 3: Cardiovascular Agents and Endocrines
ISBN 0471370290 | Wiley-Interscience, 2003 | 912 pgs | 28.14 mb
Volume 4: Autocoids, Diagnostics, and Drugs from New Biology
ISBN 0471370304 | Wiley-Interscience, 2003 | 720 pgs | 37.14 mb
Volume 5 : Chemotherapeutic Agents
ISBN 0471370312 | Wiley-Interscience, 2003 | 1125 pgs | 39.25 mb
Volume 6: Nervous System Agents
ISBN 0471274011 | Wiley-Interscience, 2003 | 1084 pgs | 48.38 mb
The Practice of Medicinal Chemistry, Second Edition (The Practice of Medicinal Chemistry)
Academic Press | 0127444815 | Edition - 2003-03-19 | PDF | 642 pages | 18.7 MB | Rapidshare & Aliceinwire
Most medicinal chemists working in the pharmaceutical industry are organic synthetic chemists with little or no background in medicinal chemistry. These chemists must acquire a good knowledge of medicinal chemistry during their first years in the pharmaceutical/drug discovery industry. This book aims to be their practical handbook - a complete guide to the drug discovery process.The book reviews practical aspects of Medicinal Chemistry, emphasising the daily problems met by the medicinal chemist when dealing with lead discovery/identification methodologies, with structure-activity relationship studies aimed to scale up potency and target selectivity, and when optimising pharmacokinetic and pharmaceutical properties by means of ultimate chemical modifications.This is the second edition of The Practice of Medicinal Chemistry, the first edition being published in February 1996. The new edition is thoroughly revised, with around 30% new material, and refocussed to reflect the recent developments in genomics, proteomics, high throughput screening of compounds and drug solubilisation. An effort has been made to remove the overlap that exists in the previous edition and four new chapters have been introduced.* Written by experts in the field* The first edition of The Practice of Medicinal Chemistry, published in 1996, was nicknamed 'The Bible' by medicinal chemists.* The only available book dealing with the practical aspects of medicinal chemistry, from conception of the molecules through to the production of drugs* An essential practical handbook for the medicinal chemist, working in the pharmaceutical industry, with little or no background in medicinal chemistry-a complete guide to the drug discovery process.DownloadLink (Uploading)orLink (Uploadbox)
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